醫療團隊
專業的醫護人員,提供最佳的醫療服務
醫師介紹
詹天明醫師
類風濕性關節炎、痛風及高尿酸血症、自體免疫性疾病、紅斑性狼瘡、修格蘭症候群、僵直性?椎炎、過敏及氣喘、血管炎、關節痛
- 國語,英語,閩南語
- 助理教授
醫師網路掛號
直接點選進入醫師網路掛號畫面
醫師資歷
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現職
- 林口長庚紀念醫院 風濕過敏免疫科 助理教授級 主治醫師
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學歷
- 長庚大學 醫學系
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經歷
- 林口長庚紀念醫院 內科部 住院醫師
- 林口長庚紀念醫院 風濕過敏免疫科 住院醫師
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學會與認證
- 臺灣醫學會
- 台灣內科醫學會
- 中華民國風濕病醫學會
- 中華民國免疫醫學會
- 中華民國醫用超音波學會
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論文及期刊發表
- Beyond co-occurrence: age, sex, and the temporal progression of autoimmune overlap syndromes in a 23-year nationwide cohort.
Semin Arthritis Rheum. 2026 Jun 3;79:153012. doi: 10.1016/j.semarthrit.2026.153012. PMID: 42269229.
Chan TM, Li PR, Luo SF, Kuo CF, See LC, et al. - Fetal-neonatal and maternal outcomes in women with Sjogren syndrome: a population-based registry linkage study.
Rheumatology (Oxford). 2023 Aug 1;62(8):2820-2828. doi: 10.1093/rheumatology/keac711. PMID: 36610986.
Chan TM, Wu CE, Yu HH, Hsiao CY, Su TH, Chen CB, Chiou MJ, Yu KH, Kuo CF. - Adverse pregnancy outcomes in women with Behcet's disease: population-based registry linkage study in Taiwan.
Clin Rheumatol. 2021 Oct;40(10):4135-4142. doi: 10.1007/s10067-021-05688-6. PMID: 33834360.
Chan TM, Chiou MJ, Kuo CF. - Risk of cancer in patients with ankylosing spondylitis: a nationwide cohort study in Taiwan.
Scand J Rheumatol. 2021;50(2):132-138. doi: 10.1080/03009742.2020.1804612.
Chan TM, Luo SF, Yu KH, See LC, Huang LH, Kuo CF. - Clinical prognosis and cancer risk assessment in autoimmune diseases with anti-TIF1γ alone or concurrent with anti-Ro52 antibodies in a Taiwanese cohort.
Clin Immunol. 2026 Feb;283:110663. doi: 10.1016/j.clim.2026.110663. PMID: 41544913.
Lee CC, Chiu LC, Lee SC, Chan TM*. - Clinical significance of anti-RP11 and anti-Ro52 antibodies in patients evaluated for systemic sclerosis: associations with interstitial lung disease and pulmonary arterial hypertension.
Joint Bone Spine. 2026 Jan;93(1):105964. doi: 10.1016/j.jbspin.2025.105964. PMID: 40921394.
Liu CH, Chiu LC, Chan TM*. - Clinical significance of cytoplasmic discrete dots (AC-18) patterns in HEp-2 cell indirect immunofluorescence: insights from a Taiwanese multicenter study.
Clin Chim Acta. 2026 Jan 1;578:120521. doi: 10.1016/j.cca.2025.120521. PMID: 40763822.
Hsiao CY, Su LJ, Yu KH, Chan TM*. - Unmasking the 'rods and rings' antinuclear antibody pattern: a sign of hepatitis C treatment and a risk factor for cerebrovascular disease.
Ann Med. 2025;57(1):2600753. doi: 10.1080/07853890.2025.2600753. PMID: 41414810.
Lin KM, Yu KH, Hsiao CY, Su YJ, Chan TM*. - Coexistence of anti-melanoma differentiation-associated protein 5 and anti-Ro52 antibodies in patients with idiopathic inflammatory myopathy: a retrospective cohort study.
Clin Rheumatol. 2025 Sep;44(9):3605-3613. doi: 10.1007/s10067-025-07562-1. PMID: 40663261.
Chen Y, Chen YF, Chiu LC, Yu KH, Chan TM*. - Distribution of antinuclear antibody patterns in patients with and without systemic lupus erythematosus: a multi-center study from Taiwan.
Formosan J Rheumatol. 2025 Jun;39(1):1-10. doi: 10.6313/FJR.202506_39(1).0001.
Chao HY, Yu KH, Chan TM*. - Risk of systemic sclerosis, pulmonary arterial hypertension, and interstitial lung disease in anti-CENP-A-positive patients with or without anti-Ro52 antibodies.
Formosan J Rheumatol. 2025 Jun;39(1):11-23. doi: 10.6313/FJR.202506_39(1).0002.
Yang YC, Yu KH, Chan TM*. - Clinical features of anti-SAE1 antibody-positive myositis and interstitial lung disease: a multicenter, retrospective study in Taiwan.
Front Immunol. 2024 Nov 7;15:1482000. doi: 10.3389/fimmu.2024.1482000. PMID: 39575249.
Hsiao CY, Tseng SC, Hsu CY, Chiu LC, Su LJ, Chan TM*. - Case report: management of Epstein-Barr virus-positive and methotrexate-associated B-cell lymphoma.
Int J Rheum Dis. 2024 Mar;27(3):e15086. doi: 10.1111/1756-185X.15086. PMID: 38443759.
Wang QA, Chan TM*. - Diagnostic utility of serum IgG4 level in IgG4-related diseases: a comprehensive systematic review and meta-analysis.
RMD Open. 2023 Dec 12;9(4):e003498. doi: 10.1136/rmdopen-2023-003498. PMCID: PMC10729036.
Chang CT, Chan TM, Yu HH, Yu KH*. - High-dose steroid and IVIG successful treatment in a case of COVID-19-associated autoimmune encephalitis: a literature review.
Front Immunol. 2023;14:1240089. doi: 10.3389/fimmu.2023.1240089. PMID: 37809102.
Liu CH, Chiu LC, Lee CC, Chan TM*. - Coexisting nodular sclerosis Hodgkin lymphoma and Kimura disease: a case report and literature review.
Int J Mol Sci. 2023 Apr 21;24(8):7666. doi: 10.3390/ijms24087666.
Lee CC, Chang SY, Teng WC, Wu CJ, Liu CH, Huang SW, Wu CE, Yu KH, Chan TM*. - Kimura's disease: a clinicopathological study of 23 cases.
Front Med (Lausanne). 2022 Dec 29;9:1069102. doi: 10.3389/fmed.2022.1069102. PMID: 36643844.
Lee CC, Yu KH, Chan TM*. - Comparison of clinical manifestations and pathology between Kimura disease and IgG4-related disease: a report of two cases and literature review.
J Clin Med. 2022 Nov 22;11(23):6887. doi: 10.3390/jcm11236887.
Chang SY, Lee CC, Chang ML, Teng WC, Hsiao CY, Yu HH, Hsieh MJ, Chan TM*. - Plasmapheresis for a patient with catatonia and systemic lupus erythematosus: a case report and literature review.
J Clin Med. 2022 Nov 10;11(22):6670. doi: 10.3390/jcm11226670. PMID: 36431144; PMCID: PMC9692717.
Tsai PS, Chen Y, Chen SY, Hsu CY, Wu JE, Lee CC, Chan TM*. - Acute respiratory distress syndrome associated with macrophage activation syndrome in systemic lupus erythematosus: a case report and literature review.
Medicine (Baltimore). 2022 Feb 4;101(5):e28612. doi: 10.1097/MD.0000000000028612. PMID: 35119005.
Chang ES, Yu HH, Wu CE, Chan TM*. - Clinicopathological and immunological features of Rowell syndrome: a retrospective cohort study.
Br J Dermatol. 2026 Jul;195(1):181-184. doi: 10.1093/bjd/ljag132. PMID: 41967127.
Wu PC, Wang CW, Chan TM, Tsai CC, Wu MY, Chung WH, Chen CB. - The risk of cardiovascular events following treatment for psoriatic arthritis with a biological agent.
Rheumatology (Oxford). 2026 Jun 3;65(6):keaf487. doi: 10.1093/rheumatology/keaf487. PMID: 41081292
Hsu CY, Lin SH, Su YJ, Tsai ML, Lin Y, Yang NI, Chan TM, Chen TH. - Clinical impact of pharmacogenetic risk variants in a large Chinese cohort.
Nat Commun. 2025 Jul 9;16(1):6344. doi: 10.1038/s41467-025-61644-x. PMID: 40634300.
Wei CY, Wen MS, Cheng CK, Sheen YJ, Yao TC, …Chan TM, …et al. - Urinary cadmium concentration is associated with the severity and clinical outcomes of COVID-19: a bicenter observational cohort study.
Environ Health. 2024 Mar 19;23(1):29. doi: 10.1186/s12940-024-01070-6. PMID: 38504259.
Chiu LC, Lee CS, Hsu PC, Li HH, Chan TM, Hsiao CC, Kuo SC, Ko HW, Lin SM, Wang CH, Lin HC, Chu PH, Yen TH. - Kimura's disease as a mimicker of cavernous hemangioma: a case report and literature review.
Int J Rheum Dis. 2024 Jan;27(1):e14858. doi: 10.1111/1756-185X.14858. PMID: 37551115.
Teng WC, Yu KH, Lee CC, Chang SC, Chang SY, Chan TM*. - Disease-modifying anti-rheumatic drugs associated with different diabetes risks in patients with rheumatoid arthritis.
RMD Open. 2023 Jul;9(3):e003045. doi: 10.1136/rmdopen-2023-003045. PMID: 37460274.
Su YJ, Chen HM, Chan TM, Cheng TT, Yu SF, Chen JF, Lin CY, Hsu CY. - Anti-mitochondrial antibody titers decrease over time in primary biliary cholangitis patients with ursodeoxycholic acid therapeutic response: a cohort study followed up to 28 years.
Front Immunol. 2022 May 19;13:869018. doi: 10.3389/fimmu.2022.869018. PMID: 35663951; PMCID: PMC9160714.
Chang ML, Chen WT, Chan TM, Lin CY, Chang MY, Chen SC, Chien RN. - Fibroblast-like synoviocytes as key regulators of homeostasis and inflammation in the joint microenvironment of inflammatory arthritis.
Biomedicines. 2026 Feb 9;14(2):396. doi: 10.3390/biomedicines14020396. PMID: 41751295.
Lee SC, Tsai PH, Chan TM, Yu KH. - Emergency department-initiated outpatient parenteral antimicrobial therapy in Taiwan: a retrospective cohort study on clinical outcomes and cost analysis.
J Microbiol Immunol Infect. 2025 Nov 14:S1684-1182(25)00194-X. doi: 10.1016/j.jmii.2025.11.001. PMID: 41253623.
Chen YK, Huang CT, Wang FL, Chan YL, Chan TM, Su TH. - Plasma phenylalanine is associated with hospital mortality in acute respiratory distress syndrome: a prospective metabolic profiling cohort study.
Eur J Med Res. 2025 Sep 2;30(1):833. doi: 10.1186/s40001-025-03043-y. PMID: 40890886.
Chiu LC, Lo CJ, Fan CM, Tang HY, Chan TM, Ko HW, et al. - Effects of mind-body interventions on immune and neuroendocrine functions: a systematic review and meta-analysis of randomized controlled trials.
Healthcare (Basel). 2025 Apr 21;13(8):952. doi: 10.3390/healthcare13080952. PMID: 40281902.
Lee SC, Tsai PH, Yu KH, Chan TM. - Ventilatory variables and computed tomography features in COVID-19 ARDS and non-COVID-19-related ARDS: a prospective observational cohort study.
Eur J Med Res. 2025 Jan 28;30(1):57. doi: 10.1186/s40001-025-02303-1. PMID: 39875972.
Chiu LC, Li HH, Juan YH, Ko HW, Kuo SCH, Lee CS, Chan TM, Lin YJ, Chuang LP, Hu HC, Kao KC, Hsu PC*. - Discriminating between homogeneous (AC-1) and dense fine speckled (AC-2) antinuclear antibody patterns: re-evaluation of immunofluorescence imaging.
Biomedicines. 2023 Nov;11(11):3027. doi: 10.3390/biomedicines11113027.
Yu HH, Hsieh PF, Huang SW, Chan TM, Tai PL, Yang ST, Yu KH. - Baricitinib treatment for palisaded neutrophilic granulomatous dermatitis: a new paradoxical reaction to tocilizumab.
Dermatitis. 2023 Sep-Oct;34(5):466-467. doi: 10.1097/DER.0000000000000879.
Chung WH, Chen CB, Chan TM. - Termbot: a chatbot-based crossword game for gamified medical terminology learning.
Int J Environ Res Public Health. 2023 Feb 26;20(5):4185. doi: 10.3390/ijerph20054185.
Hsu MH, Chan TM, Yu CS. - EGFR T751_I759delinsN mutation in exon 19 detected by NGS but not by real-time PCR in a heavily treated patient with NSCLC.
Int J Mol Sci. 2022;23(21):13451. doi: 10.3390/ijms232113451. PMID: 36362239.
Chang ZT, Chan TM, Wu CE*. - Diagnostic performance of serum IgG4 levels in patients with IgG4-related disease.
Medicine (Baltimore). 2015 Oct;94(41):e1707. doi: 10.1097/MD.0000000000001707. PMID: 26469909; PMCID: PMC4616795.
Yu KH, Chan TM, Tsai PH, Chen CH, Chang PY.
- Beyond co-occurrence: age, sex, and the temporal progression of autoimmune overlap syndromes in a 23-year nationwide cohort.