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醫療團隊

專業的醫護人員，提供最佳的醫療服務

醫師介紹

  •
蔡宗佑醫師

蔡宗佑醫師

口腔癌篩檢、診斷與外科手術治療、口咽癌與咽喉癌之診斷與手術、腮腺腫瘤與頭頸部腫瘤外科手術治療、頭頸部外科手術
  • 國語,英語,閩南語,日語
  • 助理教授
醫師網路掛號
直接點選進入醫師網路掛號畫面
醫師資歷
  • 現職
    • 林口長庚醫院 耳鼻喉頭頸外科部 助理教授級主治醫師
    • 長庚大學 醫學系 助理教授
  • 學歷
    • 長庚臨床研究所博士班進修
    • 長庚大學 醫學系 學士
  • 經歷
    • 美國德州大學安德森癌症中心(University of Texas MD Anderson Cancer Center)臨床見習
    • 美國德州大學安德森癌症中心(University of Texas MD Anderson Cancer Center)頭頸外科部門研究生
    • 林口長庚耳鼻喉部 總醫師
    • 林口長庚耳鼻喉部住院醫師
    • 第九屆國際達文西手術論壇暨手術研習（韓國延世大學）
    • 馬紹爾群島馬久羅醫院台灣衛生中心醫療替代役
  • 學會與認證
    • 台灣耳鼻喉頭頸外科 專科醫師
    • 台灣頭頸腫瘤醫學會 會員
    • 頭頸外科超音波專科醫師
    • 林口長庚醫院畢業後一般醫學訓練計畫醫師
  • 論文及期刊發表
    • Targeted inhibition of ATR kinase promotes antitumor immunity in HNSCC through enhanced STING activation and T cell function.
      Transl Oncol. 2026 Sep;71:102869. doi: 10.1016/j.tranon.2026.102869. Epub 2026 Jun 20. PMID: 42322694; PMCID: PMC13315458.
      da Costa FH, Kawabe M, Tsai TY, Okamoto K, Bartels MD, Cortes S, Veeramachaneni R, Rangel R, Frederick MJ, Sandulache VC, Sikora AG, Myers JN, Osman AA.
    • RANBP1 promotes oral cancer progression through activating YAP1 and NDUFB3 derived from the database of single-cell sequencing.
      Cancer Cell Int. 2026 Jun 10;26(1):284. doi: 10.1186/s12935-026-04361-9. PMID: 42271351; PMCID: PMC13480108.
      Yen WC, Liu SC, Jiang SS, Yang CY, Tsai FY, Liu TT, Sui YH, Li MH, Cheng HW, Yi JS, Lee CY, Wang WL, Tsai TY, Huang Y, Chang KP.
    • The SMAC-mimetic xevinapant differentially enhances cisplatin and immune checkpoint blockade efficacy in high-risk HPV-positive tumors.
      Transl Oncol. 2026 Aug;70:102839. doi: 10.1016/j.tranon.2026.102839. Epub 2026 Jun 3. PMID: 42235210; PMCID: PMC13255033.
      Tsai TY, Kawabe M, Kaga AN, Okamoto K, Myers JN, Osman AA.
    • Targeted suppression of SPP1 inhibits tumor invasion and metastasis in NRF2 hyperactivated cisplatin resistant HNSCC.
      J Transl Med. 2026 May 22;24(1):926. doi: 10.1186/s12967-026-08292-x. PMID: 42174609; PMCID: PMC13383472.
      Kawabe M, Yang S, Gomez-Bolanos LI, Takamatsu S, Flores S, Castro PD, Tsai TY, Kaga AN, Okamoto K, Frederick MJ, Sandulache VC, Kadara H, Myers JN, Osman AA.
    • Adverse Airway Events Following Head and Neck Cancer Reconstruction Without Elective Tracheostomy.
      Otolaryngol Head Neck Surg. 2026 May 22. doi: 10.1002/ohn.70293. Epub ahead of print. PMID: 42171258.
      Young TC, Tsai TY, Chan KC.
    • Longitudinal Monitoring of Pan- Immune-Inflammation Value Forecast Outcomes for Patients with Head and Neck Cancer Treated with Chemoradiotherapy or Radiotherapy: Results from a Large Cohort Study.
      Biomedicines. 2026 Apr 5;14(4):830. doi: 10.3390/biomedicines14040830. PMID: 42072371; PMCID: PMC13113991.
      Chen SH, Tsai TY, Hsieh RC, Chang KP, Kang CJ, Lu YA, Huang PW, Chen MF, Lin CY, Ding S, Tsang NM, Lu WH, Yap WK, Lin AC.
    • Effect of preventive dental treatment on caries incidence in patients receiving head and neck radiation therapy: a systematic review.
      Discov Oncol. 2026 Apr 25;17(1):745. doi: 10.1007/s12672-026-04832-5. PMID: 42033645; PMCID: PMC13190953.
      Huang SM, Huang YC, Yang SW, Young CK, Tsai TY, Lin CH, Yap WK.
    • Gland- preserving surgery versus total gland excision for benign submandibular tumors: A systematic review and meta-analysis.
      Surg Oncol. 2026 Jun;66:102433. doi: 10.1016/j.suronc.2026.102433. Epub 2026 Apr 16. PMID: 42001628.
      Lee YC, Shen EY, Chang CC, Hsin LJ, Tsai TY, Tsai YT, Lin WN, Luo CM.
    • Pretreatment nodal SUVmax predicts neck progression in hypopharyngeal cancer undergoing definitive chemoradiotherapy, while higher radiotherapy dose improves regional control particularly in the high SUV-N subgroup: a long-term outcome study.
      Am J Cancer Res. 2026 Jan 15;16(1):240-254. doi: 10.62347/EBSN4496. PMID: 41657787; PMCID: PMC12877375.
      Yap WK, Lin CH, Hsu KH, Chen PY, Lin CY, Lin SN, Cheng NM, Chang KP, Kang CJ, Young CK, Liau CT, Lu YA, Hu YF, Yeh CC, Yeh TS, Tsai TY.
    • An External Validation Study on Two Pre-Trained Large Language Models for Multimodal Prognostication in Laryngeal and Hypopharyngeal Cancer: Integrating Clinical, Treatment, and Radiomic Data to Predict Survival Outcomes with Interpretable Reasoning.
      Bioengineering (Basel). 2025 Dec 10;12(12):1345. doi: 10.3390/bioengineering12121345. PMID: 41463641; PMCID: PMC12729448.
      Yap WK, Cheng SC, Lin CH, Hsiao IT, Tsai TY, Yap WL, Chen WP, Lin CY, Huang SM.
    • Extracapsular dissection versus partial superficial parotidectomy: a systematic review and meta-analysis.
      Eur Arch Otorhinolaryngol. 2026 Mar;283(3):1895-1904. doi: 10.1007/s00405-025-09917-5. Epub 2025 Dec 22. PMID: 41430448.
      Lee YC, Lin WN, Tsai YT, Tsai TY, Fang TJ, Su SC, Luo CM, Hsieh RC, Hsin LJ.
    • Extracapsular Dissection Versus Superficial Parotidectomy: A Systematic Review and Meta-Analysis of Perioperative Efficiency.
      J Otolaryngol Head Neck Surg. 2025 Jan-Dec;54:19160216251385927. doi: 10.1177/19160216251385927. Epub 2025 Oct 31. PMID: 41170747; PMCID: PMC12579155.
      Lee YC, Hsin LJ, Tsai YT, Lin WN, Fang TJ, Su SC, Luo CM, Hsieh RC, Tsai TY.
    • Targeted suppression of SPP1 inhibits tumor invasion and metastasis in NRF2 hyperactivated cisplatin resistant HNSCC.
      bioRxiv [Preprint]. 2025 Jun14. 2025.05.28.656679. doi: 10.1101/2025.05.28.656679. Update in: J Transl Med. 2026 May 22;24(1):926. doi: 10.1186/s12967-026-08292-x. PMID: 40501947; PMCID: PMC12154876.
      Kawabe M, Yang S, Bolanos LG, Takamatsu S, Flores S, Castro PD, Tsai TY, Nishikawa-Kaga A, Frederick MJ, Sandulache V, Kadara H, Myers JN, Osman AA.
    • Tumor-width-to-tongue-width ratio: A novel predictor of cervical lymph node metastasis and prognosis in squamous cell carcinoma of the tongue.
      Oral Oncol. 2025 Jul;166:107364. doi: 10.1016/j.oraloncology.2025.107364. Epub 2025 May 15. PMID: 40378672.
      Hui Leonard TT, Yang MC, See A, Huang Y, Tsai TY, Lee CY, Huang PH, Tseng TY, Ng SH, Chang KP.
    • Pathological primary tumor status, rather than adjuvant therapy, predicts survival outcomes in pT1-3N1M0 oral cavity squamous cell carcinoma: A nationwide cohort study.
      Oral Oncol. 2025 May;164:107289. doi: 10.1016/j.oraloncology.2025.107289. Epub 2025 Apr 3. PMID: 40184884.
      Tsai YT, Wen YW, Tsai TY, Lin CY, Ng SH, Ku HY, Lou PJ, Wang CP, Lin JC, Hua CH, Lee SR, Fan KH, Chen WC, Lee LY, Chien CY, Chen TM, Terng SD, Tsai CY, Wang HM, Hsieh CH, Yeh CH, Lin CH, Tsao CK, Cheng NM, Kang CJ, Fang TJ, Huang SF, Lee LA, Fang KH, Wang YC, Lin WN, Hsin LJ, Yen TC, Liao CT.
    • PSMA2 promotes chemo- and radioresistance of oral squamous cell carcinoma by modulating mitophagy pathway.
      Cell Death Discov. 2025 Jan 10;11(1):2. doi: 10.1038/s41420-025-02286-2. PMID: 39794329; PMCID: PMC11724067.
      Wahttps://cghasp.cgmh.org.tw/webman/picture/ban_send_01.gifng CI, Chen CY, Chen TW, Cheng CC, Hong SW, Tsai TY, Chang KP.
    • Radiological Sublingual Space Invasion in Tongue Squamous Cell Carcinoma: Clinicopathological Associations and Impact on Survival.
      Otolaryngol Head Neck Surg. 2025 Mar;172(3):931-941. doi: 10.1002/ohn.1097. Epub 2024 Dec 22. PMID: 39709539.
      See A, Yang MC, Huang Y, Tsai TY, Lee CY, Huang PH, Tseng TY, Ng SH, Chang KP.
    • Postradiotherapy Response Assessment Using 18 F-FDG PET/CT in Salivary Gland Carcinoma-A Multicenter Study.
      Clin Nucl Med. 2025 Feb 1;50(2):e68-e79. doi: 10.1097/RLU.0000000000005538. Epub 2024 Oct 30. PMID: 39479972.
      Chen PY, Cheng NM, Lin CY, Chang KP, Lu YA, Tsai TY, Chen MF, Fang FM, Hsu CL, Hsieh RC.
    • Upfront Surgery Versus Upfront Concurrent Chemoradiotherapy as Primary Modality in Hypopharyngeal Squamous Cell Carcinoma: A Systematic Review and Meta- Analysis.
      J Otolaryngol Head Neck Surg. 2024 Jan-Dec;53:19160216241293633. doi: 10.1177/19160216241293633. PMID: 39468833; PMCID: PMC11528607.
      Tsai TY, Yap WK, Wang TH, Lu YA, See A, Hu YF, Huang Y, Kao HK, Chang KP.
    • Prognostic Value and Clinical Implication of Lymph Node-to-Primary Tumor SUV Ratio in Node-Positive Hypopharyngeal Squamous Cell Carcinoma Treated With Radiotherapy With or Without Chemotherapy.
      Clin Nucl Med. 2025 Jan 1;50(1):11-18. doi: 10.1097/RLU.0000000000005544. Epub 2024 Oct 17. PMID: 39441098.
      Yap WK, Lin CH, Hsu KH, Lin SN, Lin HC, Chang KP, Kang CJ, Hu YF, Shih MC, Tsai TY.
    • Postoperative radiotherapy versus surgery alone in pN1 oral cavity cancer patients: A meta-analysis.
      Tsai TY, Chiang PC, Yap WK, Huang Y, See A, Hung SY, Lu CY, Lin CY, Chang TJ, Kao HK, Chang KP.
      Laryngoscope Investig Otolaryngol. 2024 May 15;9(3):e1260. doi: 10.1002/lio2.1260. PMID: 38751691; PMCID: PMC11094775.
    • The prognostic value of lymph node to primary tumor standardized uptake value ratio in cancer patients: a meta-analysis.
      Ann Nucl Med. 2024 Aug;38(8):607-618. doi: 10.1007/s12149-024-01933-5. Epub 2024 May 9. PMID: 38724805.
      Yap WK, Hsu KH, Wang TH, Lin CH, Kang CJ, Huang SM, Lin HC, Hung TM, Chang KP, Tsai TY.
    • Vilaseca I, Peretti G. The impact of margins in laryngeal cancer patients treated with transoral laser microsurgery: a systematic review and meta- analysis.
      Eur Arch Otorhinolaryngol. 2024 Sep;281(9):4485-4494. doi: 10.1007/s00405-024-08610-3. Epub 2024 Apr 2. PMID: 38564009.
      Iandelli A, Gabella G, Marchi F, Campagnari V, Filauro M, Sampieri C, Tsai TY,
    • A Radiotherapy Dose Map-Guided Deep Learning Method for Predicting Pathological Complete Response in Esophageal Cancer Patients after Neoadjuvant Chemoradiotherapy Followed by Surgery.
      Biomedicines. 2023 Nov 16;11(11):3072. doi: 10.3390/biomedicines11113072. PMID: 38002072; PMCID: PMC10669191.
      Yap WK, Hsiao IT, Yap WL, Tsai TY, Lu YA, Yang CK, Peng MT, Su EL, Cheng SC.
    • Comments on: Value and role of surgical margins in transoral laser microsurgery of the larynx, literature review and clinical considerations.
      Eur Arch Otorhinolaryngol. 2024 Feb;281(2):1065-1066. doi: 10.1007/s00405-023-08334-w. Epub 2023 Nov 21. PMID: 37987828.
      Sampieri C, Marchi F, Campagnari V, Gabella G, Costantino A, Tsai TY, Vilaseca I, Peretti G, Iandelli A.
    • Prognostic value of interim CT-based peritumoral and intratumoral radiomics in laryngeal and hypopharyngeal cancer patients undergoing definitive radiotherapy.
      Radiother Oncol. 2023 Dec;189:109938. doi: 10.1016/j.radonc.2023.109938. Epub 2023 Oct 6. PMID: 37806562.
      Lin CH, Yan JL, Yap WK, Kang CJ, Chang YC, Tsai TY, Chang KP, Liao CT, Hsu CL, Chou WC, Wang HM, Huang PW, Fan KH, Huang BS, Tung-Chieh Chang J, Tu SJ, Lin CY.
    • Discovering the Clinical and Prognostic Role of Pan-Immune-Inflammation Values on Oral Cavity Squamous Cell Carcinoma.
      Cancers (Basel). 2023 Jan 3;15(1):322. doi: 10.3390/cancers15010322. PMID: 36612318; PMCID: PMC9818418.
      Yeh CC, Kao HK, Huang Y, Tsai TY, Young CK, Hung SY, Lu CY, Chang KP.
    • Plasma Matrix Metalloproteinase-1 as a Prognostic Biomarker in Oral Cavity Squamous Cell Carcinom.
      Cancer Manag Res. 2022 Dec 15;14:3459-3468. doi: 10.2147/CMAR.S389742
      Tsung-You Tsai , Huang-Kai Kao, Yenlin Huang , Ya-Ting Chang , Chi-Kuang Young, Shao-Yu Hung, Yu-Sun Chang, Jau-Song Yu, Kai-Ping Chang.
    • The Prognostic Value of Lymph Node Burden in Oral Cavity Cancer: Systematic Review and Meta-Analysis
      Laryngoscope. 2022 Jan;132(1):88-95. doi: 10.1002/lary.29674. Epub 2021 Jun 5.
      Tsung-You Tsai , Andrea Iandelli , Filippo Marchi , Yenlin Huang , Shiao-Fwu Tai , Shao-Yu Hung , Huang-Kai Kao , Kai-Ping Chang
    • Surgical Margins Status and Prognosis after Resection of Oral Cavity Squamous Cell Carcinoma: Results from a Taiwanese Nationwide Registry-Based Study.
      Cancers (Basel). 2021 Dec 21;14(1):15. doi: 10.3390/cancers14010015. PMID: 35008181; PMCID: PMC8749941.
      Kang CJ, Wen YW, Lee SR, Lee LY, Hsueh C, Lin CY, Fan KH, Wang HM, Hsieh CH, Ng SH, Yeh CH, Lin CH, Tsao CK, Fang TJ, Huang SF, Lee LA, Fang KH, Yen TC, Cheng NM, Tsai TY, Tai SF, Tsai CY.
    • Carcinoma Showing Thymus-like Differentiation (CASTLE) with Synchronous Papillary Thyroid Carcinoma: A Case Report and Review.
      Ear Nose Throat J. 2021 Dec 6:1455613211060167. doi: 10.1177/01455613211060167. Epub ahead of print. PMID: 34866458.
      Hsu YC, Hsueh C, Lin WN, Tsai TY, Hung SY, Lu YA.
    • Parotid Space, a Different Space from Other Deep Neck Infection Spaces.
      Microorganisms. 2021 Nov 15;9(11):2361. doi: 10.3390/microorganisms9112361. PMID: 34835486; PMCID: PMC8623793.
      Chen SL, Young CK, Liao CT, Tsai TY, Kang CJ, Huang SF.
    • Excision of Parapharyngeal Space Schwannoma with Intra-cranial Invasion Through Cervical Parotid Approach─A Case Report.
      臺灣耳鼻喉頭頸外科雜誌；52卷2期 (2017 / 06 / 01)，P79 – 82
      Tsai TY, Lin CH, Chuang CC, Chang KP
    • Bidirectional Management of a Transnasal Intracranial Chopstick Transecting Optic Nerve.
      J Craniofac Surg. 2018 Jun;29(4):e398-e402. doi:10.1097/SCS.0000000000004405.
      Tsai TY, Lee LA, Chao WC, Lee YC.
    • In Response to A Nomogram to Predict Osteoradionecrosis in Oral Cancer After Marginal Mandibulectomy and Radiotherapy.
      Laryngoscope. 2019 Oct;129(10):E344. doi: 10.1002/lary.28092. Epub 2019 May 31.
      Tsai TY, Tay ZY, Chang KP, HuangYT.
    • The role of postoperative radiotherapy in pN1 oral cavity cancer without extranodal extension.
      World J Surg Oncol. 2021 Sep 17;19(1):279. doi: 10.1186/s12957-021-02396-y. PMID: 34535149; PMCID: PMC8449449.
      Tsai TY, Huang Y, Iandelli A, Tai SF, Hung SY, Kao HK, Chang KP.
    • The Prognostic Value of Lymph Node Burden in Oral Cavity Cancer: Systematic Review and Meta-Analysis.
      Laryngoscope. 2022 Jan;132(1):88-95. doi: 10.1002/lary.29674. Epub 2021 Jun 5. PMID: 34089539.
      Tsai TY, Iandelli A, Marchi F, Huang Y, Tai SF, Hung SY, Kao HK, Chang KP.
    • A nomogram to predict osteoradionecrosis in oral cancer after marginal mandibulectomy and radiotherapy.
      Renda L, Tsai TY, Huang JJ, et al.
      Laryngoscopedoi: https://doi.org/10.1002/lary.27870.
    • The prognostic value of radiologic extranodal extension in nasopharyngeal carcinoma: Systematic review and meta-analysis.
      Oral Oncol. 2021 Nov;122:105518. doi: 10.1016/j.oraloncology.2021.105518. Epub 2021 Sep 8. PMID: 34507205
      Tsai TY, Chou YC, Lu YA, Kang CJ, Huang SF, Liao CT, Chang KP.