Expertise at Chang Gung System
  • Tel

    +886-3-3281200 ext 5150

  • E-mail
  • Address

    No.5, Fusing St., Gueishan Township, Taoyuan County 333, Taiwan (R.O.C.) / No.259, Wenhua 1st Rd., Gueishan Township, Taoyuan County 333, Taiwan (R.O.C.)

Chang, Pi-yueh

Ph.D.

  • Institution

    Chang Gung Memorial Hospital, Keelung

    Chang Gung Memorial Hospital, Linkou

    Chang Gung University

  • Position

    Deputy chief medical technologist/ Lecturer

  • Department

    Chang Gung Memorial Hospital, Keelung . Medical personnel

    Chang Gung Memorial Hospital, Linkou . Division of Laboratory Medicine

    Chang Gung University . Department of Medical Biotechnology and Laboratory Science, Graduate Institute of Medical Biotechnology and Science

  • Focus of Interes

    Medical Educate /Medical Technology, and Clinical Pathology /Molecular Biology

Fulltime Employment

1. 08/1994- present Lecturer, Department of Medical Biotechnology and Laboratory Science, Chang Gung University

2. 03/2002- 06/2008 Supervisor, Section of Research and Development, Department of Laboratory Medicine, Chang Gung Memorial Hospital

3. 12/2005- 06/2008 Supervisor, Section of Molecular Pathology, Department of Laboratory Medicine, Chang Gung Memorial Hospital

4. 07/2008- present Deputy Chief Technologist of Laboratory Medicine, Chang Gung Memorial Hospital

Education
  • 09/1988-06/1992 BS of Medical Technology, College of Medicine, National Taiwan University
  • 09/1992-06/1994 MS of Medical Technology, College of Medicine, National Taiwan University
  • 09/2010~present PHD of Medical Biotechnology and Laboratory Science, Chang Gung University
Main Publications

1. Pi-Yueh Chang, Tsu-Lan Wu, Chung-Chih Hung, Kuo-Chien Tsao, Chien-Feng Sun, Lily L. Wu and James T. Wu. Development of an ELISA for myeloperoxidase on microplate: Normal reference values and effect of temperature on specimen preparation Clin Chim Acta 2006,373: 158-163


2. Pi-Yueh Chang, Tsu-Lan Wu, Huan-Tang Chen, Kuo-Chien Tsao, Chien-Feng Sun, Lily L Wu, James T Wu. Acute inflammatory response of cosmetic liposuction causes only a transient elevation of acute inflammatory markers and does not advance to oxidative and nitrosative stress. J Clin Lab Anal 2007 ;21:418-425


3. Pi-Yueh Chang, Yung-Bin Kuo ,Tsu-Lan Wu, Chun-Ta Liao, Yu-Chen Sun, Tzu-Chen Yen , Err-Cheng Chan. Association and Prognostic Value of Serum Inflammation Markers in Patients with Leukoplakia and Oral Cavity Cancer. Clinical Chemistry and Laboratory Medicine 2013; 51(6): 1291–1300 (SCI IF= 2.955)


4. Pi-Yueh Chang, Cheng-Tao Yang, Ching-Hui Cheng, Kuang-Hui Yu. Diagnostic Performance of Anti-cyclic Citrullinated Peptide and Rheumatoid Factor in Patients with Rheumatoid Arthritis. International Journal of Rheumatic Diseases 2015. doi: 10.1111/1756-185X.12552 (SCI IF:1.771)


5. Pi-Yueh Chang, Chia-Chun Chen, Yu-Sun Chang, Wen-Sy Tsai, Jeng-Fu You, Geng-Ping Lin, Ting-Wen Chen, Jinn-Shiun Chen, Err-Cheng Chan. MicroRNA-223 and microRNA-92a in stool and plasma samples act as complementary biomarkers to increase colorectal cancer detection. Oncotarget, Advance Publications 2016; February 01

Board Certification / Professional Affiliations

-Taiwan Association of Medical Technologist, 1994 - present

-Taiwan Society of Laboratory Medicine, 1994-present

Ongoing projects
Project Role Period Grant support Budget (NTD)
Analysis of gut and fecal microbiota from patients with colorectal cancer and polyps by next generation sequencing of 16S rRNA genes PI 105/1/1-105/12/30 CGMH 712,755
Development of circulating anti-colorectal cancer associated autoantibodies and microRNAs as biomarkers for detection of colorectal cancer CO-PI 103/10/1-105/9/30 CGMH 8,000,000
Application of screening of colorectal cancer associated mutation genes by next generation sequencer CO-PI 102/8/1-105/7/31 CGMH 5,600,000
The applications of next generation sequence for gout and hyperuricemia related gene screening CO-PI 102/8/1-105/7/31 CGMH 4,800,000
Mutation screening for children with cochlear implants by using next generation sequencer CO-PI 102/8/1-105/7/31 CGMH 5,128,850