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Home > Center & Institutes > Genomic Medicine Research Core Laboratory

Introduction
  The Genomic Medicine Research Core Laboratory (GMCRL), located on the first floor of the J Building at the Lin-Kou Medical Center of Chang Gung Memorial Hospital (CGMH), was opened on May 11, 2002. Aiming to provide physician scientists and biomedical researchers of CGMH and Chang Gung University with a state-of-the-art core facility for genomic medicine research, GMCRL was the first laboratory to be established among a series of Core Laboratories in the Chang Gung System.
   
  GMRCL is equipped with the comprehensive microarray analyzing system (cDNA microarrays, Affymetrix oligonucleotide microarrays, genomic microarrays), a laser capture microdissection system, a real-time
  quantitative polymerase chain reaction (Q-PCR) system,and a mass spectrometer for matrix-assisted laser desorption/ ionization time-of-flight (MALDI-TOF) analysis (Table).

Our
research goals involving genomic medicine include understanding gene expression profile through mRNA analysis and identifying disease-associated genomic variations through examination of genomic DNA (Table). For the first goal, cDNA microarray technology, laser capture microdissection and real-time Q-PCR are employed. To complete the latter goal, genomic microarrays, Affymetrix oligonucleotide microarrays, real-time Q-PCR and MALDI-TOF will be used.

We are still recruiting researchers into GMRCL, and current personnel include (from left to right on the photo): Ding-Wei Hsueh, MS; Long-Kung Chen, MS; En-Shih Chen, MS; Tzu-Hao Wang, MD. PhD; Wei-Shiang Gong, MS; and Yun-Shien Lee, PhD.
Genomic Medicine Research Core Laboratory
 
Instrument
Technology
Research Direction
Microarray system cDNA Microarrays Identification of Gene Expression Profiles
Genomic Microarrays Analysis of Genomic
Variations
Laser Capture
Microdissection
Microdissection of Tissues Cell Type-Specific
Analysis of Gene
Expression
Real-time
Quantitative PCR
Quantitative RT-PCR
Affymetrix GeneChip Oligonucleotide
Microarrays
Validation and
Screening of Single
Nucleotide
Polymorphism
( SNP )
MALDI-TOF Mass Spectrometry
 
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