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醫療團隊

專業的醫護人員，提供最佳的醫療服務

醫師介紹

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蔡依紋醫師

蔡依紋醫師

Family medicine, Obesity medicine, Immunity, Primary care and Community medicine 家庭醫學、肥胖醫學、免疫學、社區醫學
  • 國語,英語,閩南語
  • 副教授
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醫師資歷
  • 現職
    • 林口長庚紀念醫院 家庭醫學部 部主任
    • 長庚醫院學術組副教授級主治醫師
    • 長庚大學醫學系兼任助理教授(教育部助理字第149196號)
    • 國防醫學院醫學科學研究所博士
  • 學歷
    • 國防醫學大學醫學系畢業
    • 國防醫學大學醫學科學研究所博士
  • 經歷
    • 2024/07/01~迄今 林口長庚紀念醫院 家醫部 部主任
    • 2022/07/01~2024/06/30 林口長庚紀念醫院 家醫部 副部主任 兼新北市立土城醫院(委託長庚醫療財團法人興建經營) 家醫科 科主任
    • 2016/07/01~2022/06/30 基隆長庚紀念醫院 家醫部 部主任
    • 2011/08/01~2016/07/11 林口長庚紀念醫院 家醫部 主治醫師
    • 2010/08/01~2011/07/31 林口長庚紀念醫院 家醫部 總醫師
    • 2007/07/24~2010/07/31 林口長庚紀念醫院 家醫部 住院醫師
  • 學會與認證
    • 家庭醫學專科醫師
    • 台灣肥胖醫學會 肥胖醫學專科醫師
    • 台灣安寧緩和醫學會會員及甲類安寧照護醫師
    • 台灣醫學教育學會會員
    • 103年度林口長庚紀念醫院「最佳教學優良教師」
    • 105學年度基隆長庚紀念醫院 實習醫學生「票選教學優良主治醫師」
    • 106年台灣家庭醫學學會口頭論文評選第二名
    • 110年基隆長庚紀念醫院優秀論文獎
    • 111 第十二屆臨醫所聯合研討會口頭競賽-癌症免疫組第二名
    • 114學年度林口長庚紀念醫院實習醫學生票選優良教學主治醫師
    • 115年林口長庚紀念醫院優秀論文獎
    • 115學年度林口長庚紀念醫院實習醫學生票選優良教學主治醫師
  • 論文及期刊發表
    • Blimp-1 benefits gut-homing regulatory T cells by maintaining migration/suppressive function in autoimmune diabetes-prone mice.
      Lancet eBioMedicine. Nov, 2025 ;121: 106002. (IF: 10.8)
      Yi-Wen Tsai, Yu-Wen Liu, Chao-Yuan Hsu, Shin-Huei Fu, Ming-Wei Chien, Jia-Ling Dong, Chi-Chin Sun, Chien-Tzung Chen, Huey-Kang Sytwu*
    • A Machine Learning-Based Prognostication Model Enhances Prediction of Early Hepatic Encephalopathy in Non-Cancer-Related Cirrhotic Patients- A Multi-Centre Longitudinal Cohort Study in Taiwan.
      JMIR Medical Informatics. 2025, Aug 6:13:e71229.
      Hsin-Yu Chen, Yiu-Hua Cheng, Wei-Chung Yeh, Yi-Chuan Chen, Yi-Wen Tsai*
    • Gut Microbiota-Modulated Metabolomic Profiling Shapes the Etiology and Pathogenesis of Autoimmune Diseases.
      Microorganisms, Sep 2021, 1930. https://doi.org/10.3390/microorganisms9091930 (SCI; Impact Factor=4.5; MICROBIOLOGY: 47/153)
      Yi-Wen Tsai, Jia-Ling Dong, Yun-Jie Jian, Shin-Huei Fu, Ming-Wei Chien, Yu-Wen Liu, Chao-Yuan Hsu,* and Huey-Kang Sytwu*
    • Depletion of Alpha-Melanocyte-Stimulating Hormone Induces Insatiable Appetite in Energy Reserves and Body Weight Gains in Zebrafish.
      Biomedicines, 2021 Aug. 9 (8), 941; doi: 10.3390/biomedicines9080941. (SCI; Impact Factor=4.7; BIOCHEMISTRY & MOLECULAR BIOLOGY: 92/285)
      Yang-Wen Hsieh, Yi-Wen Tsai, Hsin-Hung Lai, Chi-Yu Lai, Chiu-Ya Lin, Guor-Mour Her*
    • Palmitoleic acid ameliorates palmitic acid-induced proinflammation in J774A.1 macrophages via TLR4-dependent and TNF-α-independent signallings.
      Prostaglandins, Leukotrienes and Essential Fatty Acids, 2021 Mar 24; https:/ /doi.org/10.1016/j.plefa.2021.102270 (SCI; Impact Factor=3.00; BIOCHEMISTRY & MOLECULAR BIOLOGY: 181/285)
      Yi-Wen Tsai, Chieh-Hua Lu, Richard Cheng-An Chang, Yung-Pei Hsu, Low-Tone Ho, Kuang-Chung Shih*
    • The association between WBC count and obesity among hospital employees.
      中華職業醫學雜誌 2021. Apr 28: 123-130
      Hung-Chi Su, I-Ju Chen, Ying-Hua Shieh, Wen-zheng, Li, Wei-Chung Yeh, Yi-Wen Tsai, Jau-Yuan Chen*
    • Adipokine-Modulated Immunological Homeostasis Shapes the Pathophysiology of Inflammatory Bowel Disease.
      International Journal of Molecular Sciences, 2020 21, 9564; doi:10.3390/ijms21249564 (SCI; Impact Factor=5.6; CHEMISTRY, MULTIDISCIPLINARY: 77/230)
      Yi-Wen Tsai, Shin-Huei Fu, Jia-Ling Dong, Ming-Wei Chien, Yu-Wen Liu, Chao-Yuan Hsu*, Huey-Kang Sytwu *
    • Dipeptidyl peptidase-4 Inhibitors and the Risks of Autoimmune Diseases in Type 2 Diabetes Mellitus Patients in Taiwan: A Nationwide Population-Based Cohort Study.
      Acta Diabetologica, 2020 Apr; 1-12. doi: 10.1007/s00592-020-01533-5 (SCI; Impact Factor=3.8 ; ENDOCRINOLOGY & METABOLISM 70/145)
      Yi-Chuan Chen, Tien-Hsing Chen, Chi-Chin Sun, Jau-Yuan Chen, Shy-Shin Chang, Ling Yeung, Yi-Wen Tsai*
    • Survival prediction among patients with non cancer-related end-stage liver disease.
      PLoS One, 2018 Sep; 13(9):e0202692 (SCI; Impact Factor=3.7; MULTIDISPLINARY SCIENCES 26/73)
      Yi-Wen Tsai, I-Shiang Tzeng, Yi-Chuan Chen, Tsung-Han Hsieh, Shy-Shin Chang*
    • Dipeptidyl peptidase-4 Inhibitors and the Risks of Autoimmune Diseases in Type 2 Diabetes Mellitus Patients in Taiwan: A Nationwide Population-Based Cohort Study.Acta Diabetologica, 2020 Apr; 1-12.Yi-Chuan Chen, Tien-Hsing Chen, Chi-Chin Sun, Jau-Yuan Chen, Shy-Shin Chang, Ling Yeung, Yi-Wen Tsai*

    • Survival prediction among patients with non cancer-related end-stage liver disease.PLoS One, 2018 Sep; 13(9):e0202692.Yi-Wen Tsai, I-Shiang Tzeng, Yi-Chuan Chen, Tsung-Han Hsieh, Shy-Shin Chang*

    • Association of elevated blood serum high sensitivity C-reactive protein levels and body composition with chronic kidney disease-A population-based study in Taiwan.
      Medicine. 2018 Sep; 97(36): e11896 (SCI; Impact Factor=1.6; MEDICINE, GENERAL & INTERNAL 118/167)
      Yi-Wen Tsai, Yi-Ling Chan, Yi-Chuan Chen, Yiu-Hua Cheng, Shy-Shin Chang*
    • Visceral Adiposity Index as a Predictor of Chronic Kidney Disease in a Relatively Healthy Population in Taiwan.
      Journal of Renal Nutrition, 2018 Mar; 28(2): 91-100 (SCI; Impact Factor=3.2; UROLOGY & NEPHROLOGY 29/88)
      Yi-Chuan Chen, Shih-Han Lai, Yi-Wen Tsai*, Shy-Shin Chang*
    • Obesity, hyperhomocysteinaemia and risk of chronic kidney disease: a population-based study.
      Family Practice, 2018 May; 35(3): 259-265 (SCI; Impact Factor=2.2; MEDICINE, GENERAL & INTERNAL 103/167)
      Shih-Han Lai, Yi-Wen Tsai*, Yi-Chuan Chen, Shy-Shin Chang*
    • Risk of gastrointestinal perforation in patients taking oral fluoroquinolone therapy: An analysis of nationally representative cohort. PLoS One, 2017 Sep 5;12(9):e0183813. Shou-Chien Hsu, Shy-Shin Chang, Meng-tse Gabriel Lee, Si-Huei Lee, Yi-Wen Tsai, L Shen-Che Lin, Szu-Ta Chen, Yi-Chieh Weng, Porta Lorenzo, Jiunn-Yih Wu *

    • Risk of incident active tuberculosis disease in patients treated with non-steroidal anti-inflammatory drugs: a population-based study. BMC Pulmonary Medicine, 2017 May. 17(1): 82. Chun-Wei Wu, Jiunn-Yih Wu, Meng-Tse Gabriel Lee, Chih-Cheng Lai, I-Lin Wu, Yi-Wen Tsai, Shy-Shin Chang * and Lee CC*

    • Use of antipsychotics increases the risk of fracture: a systematic review and meta-analysis. Osteoporosis International, 2017 Apr; 28 (4):1167–1178. Lee SH, Hsu WT, Lai CC, Esmaily-Fard A, Tsai YW, Chiu CC, Wang J, Chang SS*, Lee CC*

    • Angiotensin-Converting Enzyme Inhibitors and Active Tuberculosis: A Population-Based Study. Medicine 2016 May (95) 19: e3579. Wu JY, Lee MT Gabriel, Lee SH, Lee SH, Tsai YW, Hsu SC, Change SS*, Lee CC*

    • Combined body mass index with high-sensitivity C-reactive protein as independent predictors for chronic kidney disease in a relatively healthy population in Taiwan. European Journal of Clinical Nutrition 2016; 70: 766-71. Tsai YW, Lu MC, Lin YH, Lee YC, Li WC, Chen JY and Chang SS*

    • Risk of Spontaneous Bacterial Peritonitis Associated With Gastric Acid Suppression. Medicine 2015 Jun 94 (22): e944. Change SS, Lai CC, Lee MT Gabriel, Lee YC, Tsai YW, Hsu WT, Lee CC*

    • The association of leptin and homocysteine with renal function impairment in a population of Taiwanese adults. Clinical Nutrition 2015; 34: 943-950. Chen JY, Tsai YW, Chen SY, Ho CI, Weng YM, Hsiao CT, Li WC*

    • Relationship between TG/HDL-C Ratio and Metabolic Syndrome Risk Factors with Chronic Kidney Disease in the Taiwanese Population. Clinical Nutrition 2015; 34: 874-880. Ho CI, Chen JY, Chen SY, Tsai YW, Weng YM, Tsao YC, Li WC*

    • Impact of body composition on estimated glomerular filtration rate in relatively healthy adults in Taiwan. European Journal of Clinical Nutrition 2015; 69: 34–39. Tsai YW, Ho CI, Chen JY, Chang KC, Weng YM, Chen SY, Li WC*

    • 健康促進減重活動策略之成效探討：以北部某地區醫院為例. 中華職業醫學雜誌 2015; 22卷2期, 115-121 .林士傑、曹又中、蔡依紋、張詩鑫、陳昭源*

    • 健康勞工腎臟功能下降與其危險因子之相關探討及因果分析. 中華職業醫學雜誌 2015; 22 (3): 145-153. 盧美君、陳昭源、張詩鑫、蔡依紋*

    • 移動試聽力檢查裝置作為職工噪音引起聽力缺損檢測工具可行性之研究. 中華職業醫學雜誌 2014; 21卷4期, 205-212. 陳雅鈴、陳崇賢、蔡依紋、陳昭源、陳榮祥、張詩鑫*

    • Gamma-glutamyl transpeptidase and the metabolic syndrome in a Taiwanese aboriginal population. International Journal of Diabetes in Developing Countries 2013 (33): 147-154. Ho CI, Tsao YC, Chen JY, Chang KC, Tsai YW, Lin JS, Chang SS*

    • Correlation between body composition and risk factors for cardiovascular disease and metabolic syndrome. Biofactors 2012 Jul-Aug;38(4):284-91. Chuang HH, Li WC*, Sheu BF, Liao SC, Chen JY, Chang KC, Tsai YW.

    • Impact of subjective sleep quality on glycemic control in type 2 diabetes mellitus.Family Practice 2012 Feb;29(1): 30-5.Tsai YW, Kann NH, Tung TH, Chao YJ, Lin CJ, Chang KC, Chang SS, Chen JY*

    • Analysis of Stress in an Aboriginal Populationin Taiwan: A Prospective Cross-sectional Study.中華職業醫學雜誌 2012; 19卷3期, 171-180.曹又中、何芝儀、林忠順、陳昭源、蔡依紋、張可臻、張詩鑫*

    • 某醫學中心家醫科門診三高病患藥物順應性相關因子分析.台灣家庭醫學雜誌 2011；21(1)：1-14.張可臻、周瑩婷、蔡依紋、羅錦泉、陳昭源*