DISEASES OF OTHER ENDOCRINE GLANDS (250-259)
- 250 Diabetes mellitus
- Excludes: gestational diabetes (648.8)
- hyperglycemia NOS (790.6)
- neonatal diabetes mellitus (775.1)
- nonclinical diabetes (790.2)
- that complicating pregnancy, childbirth, or the puerperium (648.0)
- The following fifth-digit subclassification is for use with category 250:
- 0 type II [non-insulin dependent type] [NIDDM type] [adult-onset type] or unspecified type, not stated as uncontrolled
- 1 type I [insulin dependent type] [IDDM] [juvenile type], not stated as uncontrolled
- 2 type II [non-insulin dependent type] [NIDDM type] [adult-onset type] or unspecified type, uncontrolled
- 3 type I [insulin dependent type] [IDDM] [juvenile type], uncontrolled
- 250.0 Diabetes mellitus without mention of complication
- Diabetes mellitus without mention of complication or manifestation classifiable to 250.1-250.9
- Diabetes (mellitus) NOS
- 250.1 Diabetes with ketoacidosis
- Diabetic:
- acidosis without mention of coma
- ketosis without mention of coma
- 250.2 Diabetes with hyperosmolarity
- Hyperosmolar (nonketotic) coma
- 250.3 Diabetes with other coma
- Diabetic coma (with ketoacidosis)
- Diabetic hypoglycemic coma
- Insulin coma NOS
- Excludes: diabetes with hyperosmolar coma (250.2)
- 250.4 Diabetes with renal manifestations
- Use additional code to identify manifestation, as:
- diabetic:
- nephropathy NOS (583.81)
- nephrosis (581.81)
- intercapillary glomerulosclerosis (581.81)
- Kimmelstiel-Wilson syndrome (581.81)
- 250.5 Diabetes with ophthalmic manifestations
- Use additional code to identify manifestation, as:
- diabetic:
- blindness (369.00-369.9)
- cataract (366.41)
- glaucoma (365.44)
- retinal edema (362.83)
- retinopathy (362.01-362.02)
- 250.6 Diabetes with neurological manifestations
- Use additional code to identify manifestation, as:
- diabetic:
- amyotrophy (358.1)
- mononeuropathy (354.0-355.9)
- neurogenic arthropathy (713.5)
- peripheral autonomic neuropathy (337.1)
- polyneuropathy (357.2)
- 250.7 Diabetes with peripheral circulatory disorders
- Use additional code to identify manifestation, as:
- diabetic:
- gangrene (785.4)
- peripheral angiopathy (443.81)
- 250.8 Diabetes with other specified manifestations
- Diabetic hypoglycemia
- Hypoglycemic shock
- Use additional code to identify manifestation, as:
- diabetic bone changes (731.8)
- Use additional E code to identify cause, if drug-induced
- Excludes: intercurrent infections in diabetic patients
- 250.9 Diabetes with unspecified complication
- 251 Other disorders of pancreatic internal secretion
- 251.0 Hypoglycemic coma
- Iatrogenic hyperinsulinism
- Non-diabetic insulin coma
- Use additional E code to identify cause, if drug-induced
- Excludes: hypoglycemic coma in diabetes mellitus (250.3)
- 251.1 Other specified hypoglycemia
- Hyperinsulinism:
- Hyperplasia of pancreatic islet beta cells NOS
- Excludes: hypoglycemia in diabetes mellitus (250.8)
- hypoglycemia in infant of diabetic mother (775.0)
- hypoglycemic coma (251.0)
- neonatal hypoglycemia (775.6)
- Use additional E code to identify cause, if drug-induced
- 251.2 Hypoglycemia, unspecified
- Hypoglycemia:
- Excludes: hypoglycemia:
- with coma (251.0)
- in diabetes mellitus (250.8)
- leucine-induced (270.3)
- 251.3 Postsurgical hypoinsulinemia
- Hypoinsulinemia following complete or partial pancreatectomy
- Postpancreatectomy hyperglycemia
- 251.4 Abnormality of secretion of glucagon
- Hyperplasia of pancreatic islet alpha cells with glucagon excess
- 251.5 Abnormality of secretion of gastrin
- Hyperplasia of pancreatic alpha cells with gastrin excess
- Zollinger-Ellison syndrome
- 251.8 Other specified disorders of pancreatic internal secretion
- 251.9 Unspecified disorder of pancreatic internal secretion
- Islet cell hyperplasia NOS
- 252 Disorders of parathyroid gland
- 252.0 Hyperparathyroidism
- Hyperplasia of parathyroid
- Osteitis fibrosa cystica generalisata
- von Recklinghausen's disease of bone
- Excludes: ectopic hyperparathyroidism (259.3)
- secondary hyperparathyroidism (of renal origin) (588.8)
- 252.1 Hypoparathyroidism
- Parathyroiditis (autoimmune)
- Tetany:
- parathyroid
- parathyroprival
- Excludes: pseudohypoparathyroidism (275.4)
- pseudopseudohypoparathyroidism (275.4)
- tetany NOS (781.7)
- transitory neonatal hypoparathyroidism (775.4)
- 252.8 Other specified disorders of parathyroid gland
- Cyst of parathyroid gland
- Hemorrhage of parathyroid gland
- 252.9 Unspecified disorder of parathyroid gland
- 253 Disorders of the pituitary gland and its hypothalamic control
- Includes: the listed conditions whether the disorder is in the pituitary or the hypothalamus
- Excludes: Cushing's syndrome (255.0)
- 253.0 Acromegaly and gigantism
- Overproduction of growth hormone
- 253.1 Other and unspecified anterior pituitary hyperfunction
- Forbes-Albright syndrome
- Excludes: overproduction of:
- ACTH (255.3)
- thyroid-stimulating hormone [TSH] (242.8)
- 253.2 Panhypopituitarism
- Cachexia, pituitary
- Necrosis of pituitary (postpartum)
- Pituitary insufficiency NOS
- Sheehan's syndrome
- Simmonds' disease
- Excludes: iatrogenic hypopituitarism (253.7)
- 253.3 Pituitary dwarfism
- Isolated deficiency of (human) growth hormone [HGH]
- Lorain-Levi dwarfism
- 253.4 Other anterior pituitary disorders
- Isolated or partial deficiency of an anterior pituitary hormone, other than growth hormone
- Prolactin deficiency
- 253.5 Diabetes insipidus
- Vasopressin deficiency
- Excludes: nephrogenic diabetes insipidus (588.1)
- 253.6 Other disorders of neurohypophysis
- Syndrome of inappropriate secretion of antidiuretic hormone [ADH]
- Excludes: ectopic antidiuretic hormone secretion (259.3)
- 253.7 Iatrogenic pituitary disorders
- Hypopituitarism:
- hormone-induced
- hypophysectomy-induced
- postablative
- radiotherapy-induced
- Use additional E code to identify cause
- 253.8 Other disorders of the pituitary and other syndromes of diencephalohypophyseal origin
- Abscess of pituitary
- Adiposogenital dystrophy
- Cyst of Rathke's pouch
- Fröhlich's syndrome
- Excludes: craniopharyngioma (237.0)
- 253.9 Unspecified
- 254 Diseases of thymus gland
- Excludes: aplasia or dysplasia with immunodeficiency (279.2)
- hypoplasia with immunodeficiency (279.2)
- myasthenia gravis (358.0)
- 254.0 Persistent hyperplasia of thymus
- 254.1 Abscess of thymus
- 254.8 Other specified diseases of thymus gland
- Atrophy of thymus
- Cyst of thymus
- Excludes: thymoma (212.6)
- 254.9 Unspecified disease of thymus gland
- 255 Disorders of adrenal glands
- Includes: the listed conditions whether the basic disorder is in the adrenals or is pituitary-induced
- 255.0 Cushing's syndrome
- Adrenal hyperplasia due to excess ACTH
- Cushing's syndrome:
- NOS
- iatrogenic
- idiopathic
- pituitary-dependent
- Ectopic ACTH syndrome
- Iatrogenic syndrome of excess cortisol
- Overproduction of cortisol
- Use additional E code to identify cause, if drug-induced
- Excludes: congenital adrenal hyperplasia (255.2)
- 255.1 Hyperaldosteronism
- Aldosteronism (primary) (secondary)
- Bartter's syndrome
- Conn's syndrome
- 255.2 Adrenogenital disorders
- Adrenogenital syndromes, virilizing or feminizing, whether acquired or associated with congenital adrenal hyperplasia consequent on inborn enzyme defects in hormone synthesis
- Achard-Thiers syndrome
- Congenital adrenal hyperplasia
- Female adrenal pseudohermaphroditism
- Male:
- macrogenitosomia praecox
- sexual precocity with adrenal hyperplasia
- Virilization (female) (suprarenal)
- Excludes: adrenal hyperplasia due to excess ACTH (255.0)
- isosexual virilization (256.4)
- 255.3 Other corticoadrenal overactivity
- Acquired benign adrenal androgenic overactivity
- Overproduction of ACTH
- 255.4 Corticoadrenal insufficiency
- Addisonian crisis
- Addison's disease NOS
- Adrenal:
- atrophy (autoimmune)
- calcification
- crisis
- hemorrhage
- infarction
- insufficiency NOS
- Excludes: tuberculous Addison's disease (017.6)
- 255.5 Other adrenal hypofunction
- Adrenal medullary insufficiency
- Excludes: Waterhouse-Friderichsen syndrome (meningococcal) (036.3)
- 255.6 Medulloadrenal hyperfunction
- Catecholamine secretion by pheochromocytoma
- 255.8 Other specified disorders of adrenal glands
- Abnormality of cortisol-binding globulin
- 255.9 Unspecified disorder of adrenal glands
- 256 Ovarian dysfunction
- 256.0 Hyperestrogenism
- 256.1 Other ovarian hyperfunction
- Hypersecretion of ovarian androgens
- 256.2 Postablative ovarian failure
- Ovarian failure:
- iatrogenic
- postirradiation
- postsurgical
- 256.3 Other ovarian failure
- Premature menopause NOS
- Primary ovarian failure
- 256.4 Polycystic ovaries
- Isosexual virilization Stein-Leventhal syndrome
- 256.8 Other ovarian dysfunction
- 256.9 Unspecified ovarian dysfunction
- 257 Testicular dysfunction
- 257.0 Testicular hyperfunction
- Hypersecretion of testicular hormones
- 257.1 Postablative testicular hypofunction
- Testicular hypofunction:
- iatrogenic
- postirradiation
- postsurgical
- 257.2 Other testicular hypofunction
- Defective biosynthesis of testicular androgen
- Eunuchoidism:
- Failure:
- Leydig's cell, adult
- seminiferous tubule, adult
- Testicular hypogonadism
- Excludes: azoospermia (606.0)
- 257.8 Other testicular dysfunction
- Goldberg-Maxwell syndrome
- Male pseudohermaphroditism with testicular feminization
- Testicular feminization
- 257.9 Unspecified testicular dysfunction
- 258 Polyglandular dysfunction and related disorders
- 258.0 Polyglandular activity in multiple endocrine adenomatosis
- 258.1 Other combinations of endocrine dysfunction
- Lloyd's syndrome
- Schmidt's syndrome
- 258.8 Other specified polyglandular dysfunction
- 258.9 Polyglandular dysfunction, unspecified
- 259 Other endocrine disorders
- 259.0 Delay in sexual development and puberty, not elsewhere classified
- 259.1 Precocious sexual development and puberty, not elsewhere classified
- Sexual precocity:
- NOS
- constitutional
- cryptogenic
- idiopathic
- 259.2 Carcinoid syndrome
- Hormone secretion by carcinoid tumors
- 259.3 Ectopic hormone secretion, not elsewhere classified
- Ectopic:
- antidiuretic hormone secretion [ADH]
- hyperparathyroidism
- Excludes: ectopic ACTH syndrome (255.0)
- 259.4 Dwarfism, not elsewhere classified
- Dwarfism:
- Excludes: dwarfism:
- achondroplastic (756.4)
- intrauterine (759.7)
- nutritional (263.2)
- pituitary (253.3)
- renal (588.0)
- progeria (259.8)
- 259.8 Other specified endocrine disorders
- Pineal gland dysfunction
- Progeria
- Werner's syndrome
- 259.9 Unspecified endocrine disorder
- Disturbance:
- endocrine NOS
- hormone NOS
- Infantilism NOS